Anti-RCC1 antibody
Product Name Anti-RCC1 antibody
Catalog No PAab07209
Packing 100ug
Form liquid
Alternative Name CHC1
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly.
Immunogen regulator of chromosome condensation 1
Specificity Human,Mouse ,Rat, Monkey
Tested Application ELISA,WB,IHC,IP,IF
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human ovary tumor usingSNHG3-RCC1 antibody at dilution of 1:100
WB use
MCF7 cells were subjected to SDS PAGE followed by western blot with PAab07209(SNHG3-RCC1 antibody) at dilution of 1:300
Protein Information
Gene ID751867
Uniprot ID P18754
Calculated MW
location