Anti-RGS2 antibody

Product Name Anti-RGS2 antibody

Catalog No PAab07269

Packing 100ug

Form liquid

Alternative Name G0S8

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).

Immunogen regulator of G-protein signaling 2, 24kDa

Specificity Human

Tested Application ELISA,WB,IHC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human pancreas cancer usingRGS2 antibody at dilution of 1:50

WB use

fetal human brain tissue were subjected to SDS PAGE followed by western blot with PAab07269( RGS2 Antibody) at dilution of 1:600

Protein Information

Gene ID5997

Uniprot ID P41220

Calculated MW

location