Anti-RGS2 antibody
Product Name Anti-RGS2 antibody
Catalog No PAab07269
Packing 100ug
Form liquid
Alternative Name G0S8
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).
Immunogen regulator of G-protein signaling 2, 24kDa
Specificity Human
Tested Application ELISA,WB,IHC
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human pancreas cancer usingRGS2 antibody at dilution of 1:50
WB use
fetal human brain tissue were subjected to SDS PAGE followed by western blot with PAab07269( RGS2 Antibody) at dilution of 1:600
Protein Information
Gene ID5997
Uniprot ID P41220
Calculated MW
location