Anti-RRAGB antibody

Product Name Anti-RRAGB antibody

Catalog No PAab07488

Packing 100ug

Form liquid

Alternative Name

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates to the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.

Immunogen Ras-related GTP binding B

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human brain tissue slide using RRAGB Antibody at dilution of 1:50

WB use

human testis tissue were subjected to SDS PAGE followed by western blot with PAab07488(RRAGB antibody) at dilution of 1:500

Protein Information

Gene ID10325

Uniprot ID Q5VZM2

Calculated MW

location