Anti-RYK antibody
Product Name Anti-RYK antibody
Catalog No PAab07548
Packing 100ug
Form liquid
Alternative Name JTK5A
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Immunogen RYK receptor-like tyrosine kinase
Specificity Human,Mouse ,Rat
Tested Application ELISA,WB,IHC
Recommended dilution WB:1:500-1:5000;IHC:1:20-1:200;IF:1:20-1:200
IHC use
Immunohistochemistry of paraffin-embedded human kidney usingRYK antibody at dilution of 1:50
WB use
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab07548(RYK antibody) at dilution of 1:1000
Protein Information
Gene ID6259
Uniprot ID P34925
Calculated MW 68kDa
location