Anti-SAMHD1 antibody

Product Name Anti-SAMHD1 antibody

Catalog No PAab07592

Packing 100ug

Form liquid

Alternative Name MOP5

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.

Immunogen SAM domain and HD domain 1

Specificity Human, Mouse ,Rat

Tested Application ELISA,WB,IHC,IP,FC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human lung cancer usingSAMHD1 antibody at dilution of 1:50

WB use

HepG2 cells were subjected to SDS PAGE followed by western blot with PAab07592(SAMHD1 antibody) at dilution of 1:1000

Protein Information

Gene ID25939

Uniprot ID Q9Y3Z3

Calculated MW

location