Anti-TNFAIP1 antibody

Product Name Anti-TNFAIP1 antibody

Catalog No PAab08816

Packing 100ug

Form liquid

Alternative Name BACURD2 antibody, EDP1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.

Immunogen tumor necrosis factor, alpha-induced protein 1 (endothelial)

Specificity Human,Mouse ,Rat

Tested Application ELISA,IHC,WB,IF

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human placenta usingTNFAIP1 antibody at dilution of 1:50

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab08816(TNFAIP1 antibody) at dilution of 1:500

Protein Information

Gene ID7126

Uniprot ID Q13829

Calculated MW

location