Anti-XRP2 antibody

Product Information
Catalog No.:    LSMab09990
Size:    100μg
Form:    liquid
Purification:    Immunogen affinity purified
Purity:    ≥95% as determined by SDS-PAGE
Host:    Rabbit
IsoType:    IgG
Storage:    PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background
Acts as a GTPase-activating protein(GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119(or UNC119B). Acts as a GTPase-activating protein(GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.

Immunogen information
Immunogen:    retinitis pigmentosa 2
Synonyms:    DELXp11.3, KIAA0215, Protein XRP2, RP2, TBCCD2
Calculated MW:    40 kDa
Uniprot ID :    O75695

Application
Specificity:    Human; other species are not tested. Please decide the specificity by homology
Tested Application:    ELISA, WB, IHC
Recommended dilution:    WB: 1:500-1:2000; IHC: 1:50-1:500

Validation :

Immunohistochemistry of paraffin-embedded human intestinal cancer using LSMab09990(XRP2 antibody) at dilution of 1:100
 

Jurkat cells were subjected to SDS PAGE followed by western blot with LSMab09990(XRP2 antibody) at dilution of 1:1000