Anti-ZC3H8 antibody

Product Name Anti-ZC3H8 antibody

Catalog No PAab09605

Packing 100ug

Form liquid

Alternative Name Fliz1 antibody, ZC3H8 antibody, ZC3HDC8

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Immunogen zinc finger CCCH-type containing 8

Specificity Human

Tested Application ELISA,WB

Recommended dilution WB:1:1000-1:10000

IHC use

WB use

K-562 cells were subjected to SDS PAGE followed by western blot with PAab09605( ZC3H8 Antibody) at dilution of 1:2000

Protein Information

Gene ID84524

Uniprot ID Q8N5P1

Calculated MW 34kDa

location