Anti-ZEB1 antibody

Product Name Anti-ZEB1 antibody

Catalog No PAab09620

Packing 100ug

Form liquid

Alternative Name AREB6 antibody, BZP antibody, DELTA EF1 antibody, delta EF1 antibody, antibody, Negative regulator of IL2 antibody, NIL 2 A antibody, NIL 2 A zinc finger protein antibody, NIL 2A antibody, NIL2A antibody, TCF 8 antibody, TCF8 antibody, Transcription factor 8 antibody, ZEB antibody, ZEB1 antibody, ZFHEP antibody, ZFHX1A

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.

Immunogen zinc finger E-box binding homeobox 1

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IP

Recommended dilution WB : 1:500-1:5000;IP:1:200-1:2000

IHC use

WB use

MCF7 cells were subjected to SDS PAGE followed by western blot with PAab09620(ZEB1 antibody) at dilution of 1:500

Protein Information

Gene ID6935

Uniprot ID P37275

Calculated MW 124kDa,Observed 210kDa

location