Porcine IFN- Beta/ IFNB ELISA Kit

Product Name:Porcine IFN- Beta/ IFNB ELISA Kit
Packing:96T

Catalog No.:ELA-E0222p

Target Name:Porcine IFN-Beta/ IFNB

Detect Range: 31.25 pg/mL - 2000 pg/mL. The standard curve concentrations used for the ELISA’s were 2000 pg/mL, 1000 pg/mL, 500 pg/mL, 250 pg/mL, 125 pg/mL, 62.5 pg/mL, 31.25 pg/mL, 0 pg/mL.

Sensitivity: The limit of detection of Porcine INTERFERON BETA  defined as the analyte concentration resulting in an absorbance significantly higher than that of the dilution medium (mean plus 2 standard deviations) was determined to be 10.4pg/mL (mean of 6 independent assays).

Protein Name:Porcine IFN-Beta/ IFNB

Alternative Name:IFN-Beta/ IFNB
Sample type:serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

ELISA type:Sandwich ELISA Kit

Product Description: Porcine Interferon Beta ELISA Kit is for the quantitative detection ofPorcine Interferon Beta concentration in serum, plasma and other biological fluids.

IFN beta Description

IFN beta elicits a markedly higher antiproliferation response in some cell types such as, embryonal carcinoma, melanoma and melanocytes than do IFN alphas. Higher potency of IFN beta in treatment of multiple sclerosis and certain cancers has been observed. Type I IFNs signal through binding to a common cell surface receptor. Two chains of the receptor, IFNAR1 and IFNAR2, have been identified. 4 Both chains are necessary for function and in the absence of either there is neither high affinity binding nor biological activity. The intracellular portions of the receptor subunits are bound by tyrosine kinases, Jak1 and Tyk2, members of the Janus kinase family. Upon ligand binding these kinases are activated and phosphorylate members of the STAT family of transcription factors, as well as IFNAR1 and 2.

NOTE:FOR RESEARCH USE ONLY; NOT FOR THERAPEUTIC OR DIAGNOSTIC APPLICATIONS! PLEASE READ ENTIRE PROCEDURE!