Anti-ID3 antibody

Product Name Anti-ID3 antibody

Catalog No PAab04115

Packing 100ug

Form liquid

Alternative Name 1R21 antibody, BHLHB25 antibody, HEIR1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer.

Immunogen inhibitor of DNA binding 3, dominant negative helix-loop-helix protein

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB

Recommended dilution

IHC use

WB use

Protein Information

Gene ID3399

Uniprot ID Q02535

Calculated MW

location