Anti-RASGRP2 antibody

Product Name Anti-RASGRP2 antibody

Catalog No PAab07132

Packing 100ug

Form liquid

Alternative Name CDC25L antibody, MCG7

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.

Immunogen RAS guanyl releasing protein 2 (calcium and DAG-regulated)

Specificity Human, Mouse

Tested Application ELISA,WB

Recommended dilution

IHC use

WB use

Protein Information

Gene ID10235

Uniprot ID Q7LDG7

Calculated MW

location