Anti-FBLIM1 antibody

Product Name Anti-FBLIM1 antibody

Catalog No PAab03028

Packing 100ug

Form liquid

Alternative Name FBLP1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin- containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.

Immunogen filamin binding LIM protein 1

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human lung cancer usingFBLIM1 antibody at dilution of 1:100

WB use

HepG2 cells were subjected to SDS PAGE followed by western blot with PAab03028(FBLIM1 antibody) at dilution of 1:500

Protein Information

Gene ID54751

Uniprot ID Q8WUP2

Calculated MW

location