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Product Name Anti-FBLIM1 antibody
Catalog No PAab03028
Packing 100ug
Form liquid
Alternative Name FBLP1
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin- containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.
Immunogen filamin binding LIM protein 1
Specificity Human,Mouse ,Rat
Tested Application ELISA,WB,IHC
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human lung cancer usingFBLIM1 antibody at dilution of 1:100
WB use
HepG2 cells were subjected to SDS PAGE followed by western blot with PAab03028(FBLIM1 antibody) at dilution of 1:500
Protein Information
Gene ID54751
Uniprot ID Q8WUP2
Calculated MW
location
English
